Mequinol

Mequinol, also known as 4-Methoxyphenol, is a skin-brightening active ingredient used in cosmetic formulations designed to improve the appearance of uneven skin tone and discoloration. It works by helping to reduce the formation of excess melanin in the skin, making it a valuable ingredient in products targeting hyperpigmentation, dark spots, age spots, post-inflammatory pigmentation, and uneven complexion.

Mequinol is often incorporated into advanced brightening and skin-tone-evening formulations due to its effectiveness in promoting a more uniform and radiant appearance.

INCI Name: Mequinol

Functions

Skin Brightening Agent

Skin Tone Correcting Active

Pigmentation Management Active

Cosmetic Depigmenting Agent

Skin Conditioning Agent

Solubility

Soluble in alcohol

Slightly soluble in water

Soluble in glycols and certain cosmetic solvents

Recommended Usage Rate

0.1–2%

Typical Usage:

Spot treatment products: 0.5–2%

Brightening serums: 0.1–1%

Corrective creams: 0.5–2%

Always conduct stability and compatibility testing before commercial production.

pH Stability

Recommended formulation pH: 4.0–6.5

Best incorporated into formulations within this pH range for optimal stability.

Formulation Guidelines

Add during the cool-down phase.

Protect formulations from excessive light and air exposure.

Often combined with complementary brightening ingredients and antioxidants.

Conduct stability testing when formulating with oxidizable ingredients.